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Uniform regions (solid backgrounds, smooth gradients) get stored as large blocks. Detailed regions (edges, textures) get subdivided into smaller blocks. You end up with a compressed representation that preserves detail where it exists and simplifies where it can.
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If you deal with discomfort from working at a computer all day, ergonomic keyboards can help. These specially designed boards re-orient the keys, allowing you to hold your elbows farther apart and maintain a straighter line from your forearms to hands. Some people find this subtle change more comfortable.